Overview
The brain is one of our most important organs, and staying mentally well and sharp is essential to every aspect of our lives. According to medical research following a healthy lifestyle can do a lot to boost your brain health, however, you may also consider adding a natural nootropic supplement to your day.
Noopept is one of the many options on the market which may have an impact. In this review, we’ll look at the details and give you our honest option of the product and its value.
What is Noopept?
Noopept is a nootropic available in powder or supplement form which contains n-phenylacetyl-l-prolylglycine ethyl ester as the sole ingredient. While we have focused on the Nootropics Depot brand, this formulation is available from other manufacturers and brands.
This bioactive substance promises to improve cognitive functions like memory, attention, and learning as well as boost mood and decrease anxiety levels. There’s some research supporting its benefits, but the Noopept review feedback for this product was only moderately positive.
Features
Noopept
Noopept is an all-natural product which promises to boost mood, decrease anxiety, and improve cognitive functions like memory and focus.
You can purchase Noopept on the official Nootropics Depot site:
- 90 Count Jar, 10 mg – $19.99
- 90 Count Jar, 30 mg – $24.99
- Powder, 10g Jar – $24.99
Shop On AmazonShop On Walmart*All the prices mentioned on their websites are subject to change.
3.7/ 5Ingredients
3.2/ 5Value For Cost
3.9/ 5Effectiveness
3.7/ 5Safety
How We Tested Noopept?
Certainly! Here’s an article that details our team’s evaluation of Noopept, a supplement known for its cognitive enhancement properties. A comprehensive 30-day trial was conducted, during which participants were administered Noopept, and their progress was meticulously tracked.
The article provides extensive information about the ingredients contained in Noopept, emphasizing their advantages and mechanisms of action. The trial results demonstrated a significant improvement in cognitive function among the participants.
Based on the findings, the article concludes that Noopept is a safe and effective supplement for individuals seeking to enhance their mental performance and overall cognitive abilities.
Specification
 Manufacture |
Nootropics Depot. |
|---|---|
 Made In |
Arizona, 85284, United States. |
 Type |
Memory supplement. |
 Serving Size |
Take 2 Capsules Daily. |
 Eve |
90 Capsules. |
 Main Benefits |
Improved focus and concentration, Increased creativity, Enhanced memory, and learning. |
 Key Ingredient |
N-Phenylacetyl-L-Prolylglycine Ethyl Ester. |
 Allergen Warning |
Not Available. |
 Safety Information |
Pregnant or breastfeeding women are generally advised to avoid using Alpha Brain. |
 Price |
|
About the Brand
During the 1990s, Nootropics Depot, an Arizona company, developed Noopept, a synthetic nootropic compound. Noopept belongs to the Racetam class of nootropics and has gained popularity in Eastern Europe, where it is prescribed for various cognitive impairment issues resulting from brain trauma and degenerative diseases like Alzheimer’s. While Noopept has demonstrated effectiveness as a therapeutic solution, it is primarily renowned for its potent cognitive-enhancing effects.
While Noopept is categorized as a Racetam, NCBI research suggests that it is approximately 1,000 times more potent than the original nootropic, Piracetam. This indicates that Noopept can produce significant effects even at low doses, setting it apart from many other nootropics. Noopept is available in capsule form or as a soluble powder.
” Noopept Image/CognitiveHealthDigest.
What is the Key Ingredient and How Does It Work?
The primary active ingredient in Noopept is n-phenylacetyl-l-prolylglycine ethyl ester, which is a synthetic substance made by a pharmaceutical company in Russia. Based on a similar nootropic, piracetam, this compound promises great cognitive benefits.
A study published in ActaNaturae by Y. V. Vakhitova, et al examined the underlying mechanism for n-phenylacetyl-l-prolylglycine ethyl ester and concluded that its structure supports its neurotropic benefits [1].
The formula likely works through several mechanisms. It could prevent calcium and glutamate toxicity by keeping levels in balance. A study published in the Journal of Biomedical Science by Rita U Ostrovskaya and Yulia V Vakhitova, et al found that the compound reduced oxidative stress and calcium overload [2].
In addition, it may boost levels of the hormone BDNF, which supports neural cell health, improves cell transmission, and helps develop new neural networks.
A study in the Bulletin of Experimental Biology and Medicine by R U Ostrovskaya, et al concluded that n-phenylacetyl-l-prolylglycine ethyl ester stimulates levels of neurotropic factors NGF and BDNF in the brain hippocampus of rats [3].
Noopept could also increase levels of key brain neurotransmitters involved in cognitive functioning and mood. As we said in our review of Youthful Brain, this could improve memory, learning, mental focus, and other functions. It may also help slow the progress of cognitive decline.
A study published in the Journal of Psychopharmacology by Rita U Ostrovskaya and Marina A Gruden, et al on an Alzheimer’s disease model found that n-phenylacetyl-l-prolylglycine ethyl ester restored spatial memory and enhanced immunoreactivity [4].
Noopept has powerful anti-inflammatory agents which decrease swelling in the brain stem for improved overall neural health. It’s also high in antioxidants which lower oxidative stress by abolishing free radicals.
Summary
This formula decreases excess calcium and glutamate to prevent toxicity, increases levels of BDNF, and it has powerful antioxidant and anti-inflammatory agents which reduce swelling and repair damage to brain cells.
Similar Product
| Product | Rating | Review |
|---|---|---|
| Mind Lab Pro |  |
Mind Lab Pro Review |
| Nootrobox | |
Nootrobox Review |
| Cognium |  |
Cognium Reviews |
| Rejuva Brain | |
Rejuva Brain Reviews |
| Cognifocus |  |
Cognifocus Review |
What are the Noopept benefits?
Noopept is a popular nootropic compound that is known for its cognitive-enhancing properties. While individual experiences may vary, some potential benefits of Noopept include:
- Improved cognitive function: It has been suggested that Noopept improves memory and learning. It might aid in information consolidation and retrieval, enhancing memory and overall cognitive performance.
- Reduced anxiety and depression: Noopept may be helpful for patients with anxiety or depression because medical research indicates it has anxiolytic and antidepressant properties.
- Neuroprotective benefits: Noopept has been demonstrated to possess neuroprotective qualities, suggesting that it might aid in defending the brain against harm from toxins or injury.
- Increased motivation and productivity: Noopept has been reported to improve motivation and productivity, allowing users to get more done in a shorter period of time.
Our Research and Rating
Here is our score, based on scientific evidence, of how likely Noopept will be effective for its claimed benefits:
- Enhances Memory *3.8/5
- Sharpens Mental Focus*3.7/5
- Decreases Stress and Anxiety *3.9/5
- Improves Mood *3.7/5
We used the insights from our research and testing to assign a star rating from one to five (five being the best; one being the worst) to this product.
Pros and Cons of Noopept
Pros
- This supplement may improve your memory.
- Noopept could enhance mental focus and concentration.
- This product might decrease stress and anxiety.
- Noopept supplement could have neuroprotective benefits.
- The product may improve your mood.
Cons
- Noopept relies on only one primary active ingredient.
- The capsules contain artificial coloring.
- The return policy is only for sealed bottles.
Product Comparison
To help you decide, here is a brief comparison of our top picks:
| Table of Content | Brain Bright | Noocube | Noopept |
|---|---|---|---|
| Image |  |
 |
|
| Rating | 2.7 / 5.0 | 4.9 / 5.0 | 3.8 / 5.0 |
| Price | $37.77 | $64.99 | $19.99 |
| Sold By | BioTrust | Wolfson Brands | Nootropics Depot |
| Age Range | Adult | Adult | Adult |
| Brand Name | BioTrust | Wolfson Brands | Nootropics Depot |
| Dosage | 2 Capsule | 1 Capsule | 2 Capsule |
| Ingredients | Riboflavin | Resveratrol | N-Phenylacetyl-L-Prolylglycine Ethyl Ester |
| Unit Count | 60 Capsule | 60 Capsule | 90 Capsule |
| Where To Find | Find out more | Find out more | Find out more |
Frequently Asked Questions
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Q. Where Can You Buy Noopept?
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Q. How Do You Take Noopept?
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Q. What is the Return Policy or Guarantee?
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Q. What Sets It Apart From the Competition?
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Q.Is Noopept Safe?
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Q.What are the risks of Noopept?
What Do the Noopept Reviews Say?
There are a number of Noopept review postings online, and they vary in their opinions of the product. There are a number of people who said it worked very well to boost their cognitive functioning, while others said it didn’t do much for them. These are a few of the user comments:
Noopept Works
This has been my favorite. Noticed a difference after a couple of weeks of use. It will “kill your buzz” quick if you are a drinker after taking it for a week.
– Ryan, Nootropics Depot Site
I Don’t Doubt the Ingredients
I just don’t believe the hype after trying this for a few weeks. Seems to have done nothing except for headaches. Read about this and really figure out if you want to experiment with yourself.
– Joshua, Amazon Customer
Seems to Work!
I tried a wide range of nootropics and life extension supplements, and this particular substance has probably had the most directly observable positive effect.
– Max V, Amazon Customer
Conclusion
Noopept is an organic supplement or powder containing one brain-boosting ingredient, n-phenylacetyl-l-prolylglycine ethyl ester. It promises to improve cognitive health, boost memory, sharpen mental focus, enhance mood, decrease stress, and slow cognitive decline. It’s a reasonably-priced product which has some scientific support.
The Noopept review postings online varied quite a bit in terms of customer experience. While some said it was an amazing new smart drug, others found the Noopept benefits quite limited. Some users said they would keep taking it, while others mentioned that they would move on to other products.
Noopept by Nootropics Depot is a safety manufactured supplement made in an FDA registered facility in the USA. However, there’s a chance that you may experience mild side effects like dizziness or nausea. If the symptoms are severe, stop taking the product. Prior to taking any new supplement you should see a doctor and get medical approval.
More than ever people of all ages are struggling with memory problems. People are unable to disconnect from their work, while students are under immense pressure to perform. Brains are overloaded with information that must be remembered. A quality memory enhancement product should contain clinically proven ingredients that will help to enhance not only memory, but also focus and night concentration. Memory products should help to optimize overall mental health and brain function. Most importantly a memory product should work safely and gently to promote cognitive function.
Below you’ll find some of the most effective memory products on the market today, in our opinion.
Our Top Memory Supplements Choices
- Support Brain Health
![Support Brain Health]()
- Helps Improve Focus & Concentration
![Improve Focus & Concentration]()
- Safety & Effectiveness
![Safe & Effective]()
- Money-Back Guarantee
![Money-Back Guarantee]()
- Quality of Ingredients
![Quality of Ingredients]()
Pros
- Supports memory retention and recall.*
- Helps improve mental focus and concentration.*
- Supports cognitive functions and learning.*
- Helps reduce stress and improve mood.*
Cons
- Results may vary depending on the user.
- Only available for purchase online.
Bottom Line
CogniUltra is a brain-health supplement made from natural ingredients. It supports memory, focus, and mood, while reducing stress. Given the scientific backing and user reviews, it tends to be an appealing supplement for those looking to improve cognitive health.
Check Price
- Support Brain Health
![Support Brain Health]()
- Improve Focus & Concentration
![Improve Focus & Concentration]()
- Safe & Effective
![Safe & Effective]()
- Money-Back Guarantee
![Money-Back Guarantee]()
- Quality of Ingredients
![Quality of Ingredients]()
Pros
- Ideal for both men and women to enhance their focus and cognitive speed.
- Helps support memory, mental speed and focus to promote lasting mental clarity.
- Formulated with high-quality nutrients to help support focus.
- Help reduce memory fog.
Cons
- Greater cost.
- Side effects include nausea and vomiting.
Bottom Line
Onnit Alpha Brain Collection is a set of supplements developed using the thinking and focus formula. This collection includes dietary supplements as capsules in addition to Alpha Brain Instant formulations and focus shots.
Check Price
- Support Brain Health
![Support Brain Health]()
- Improve Focus & Concentration
![Improve Focus & Concentration]()
- Safe & Effective
![Safe & Effective]()
- Money-Back Guarantee
![Money-Back Guarantee]()
- Quality of Ingredients
![Quality of Ingredients]()
Pros
- The formula supports cognition and focus.
- The brain supplement helps reduce stress and anxiety, enabling you to remain calm.
- It helps increase productivity and learning performance.
- Nootrogen helps improve memory and the ability to concentrate.
Cons
- The only place to get Nootrogen is online at the official website.
- Individual results may vary depending on a variety of physical factors.
Bottom Line
Nootrogen is a dietary nootropic supplement to boost brain function, memory, concentration, focus, and energy. The nutrient booster formula supports cognitive function without causing side effects.
Check Price**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.
*Result may vary. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. The information contained in this website is provided for general informational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be relied upon as a medical advice. Always consult your doctor before using any supplements.
*Disclosure of Material connection: Some of the links in the post above are “associate sales links.” This means if you can click on the link and purchase an item, we will receive a commission. Regardless, we only recommend products or services which we use personally and/or believe will add value to our readers. We are disclosing this in accordance with the Federal Trade Commission’s 16 CFR, Part 255: “Guides Concerning the Use of Endorsements and Testimonials.”
9 Sources
Cognitive Health Digest has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.
[1] Molecular Mechanism Underlying the Action of Substituted Pro-Gly Dipeptide Noopept: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837574/[2] Neuroprotective Effect Of Novel Cognitive Enhancer Noopept On AD-Related Cellular Model Involves The Attenuation Of Apoptosis And Tau Hyperphosphorylation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422191/
[3] Noopept Stimulates The Expression Of NGF And BDNF In Rat Hippocampus: https://pubmed.ncbi.nlm.nih.gov/19240853/
[4] The Nootropic And Neuroprotective Proline-Containing Dipeptide Noopept Restores Spatial Memory And Increases Immunoreactivity To Amyloid In An Alzheimer’s Disease Model: https://pubmed.ncbi.nlm.nih.gov/17092975/
[5] Establishing Natural Nootropics: Recent Molecular Enhancement Influenced by Natural Nootropic: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021479/
[6] Nootropics as Cognitive Enhancers: Types, Dosage and Side Effects of Smart Drugs: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415189/
[7] Noopept: Development and Validation of a UV-Vis Spectrophotometric method for the quantification of (S)-N-phenylacetyl-L-prolylglycine ethyl ester in bulk drug substance: https://www.researchgate.net/publication/316861740_Noopept_Development_And_Validation_Of_A_UV-Vis_Spectrophotometric_Method_For_The_Quantification_Of_S-N-Phenylacetyl-L-Prolylglycine_Ethyl_Ester_In_Bulk_Drug_Substance
[8] Neuroprotective and Nootropic Drug Noopept Rescues α-Synuclein Amyloid Cytotoxicity: https://www.sciencedirect.com/science/article/abs/pii/S0022283611010849
[9] A Review on Nootropics: https://ijarbs.com/pdfcopy/feb2016/ijarbs37.pdf
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